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Modulation of doxorubicin-induced expression of the multidrug resistance gene in breast cancer cells by diltiazem and protection against cardiotoxicity in experimental animals

BACKGROUND: Doxorubicin (DOX) is one of the most important anticancer agents used in treating breast cancer. However, chronic cardiotoxicity and multidrug resistance limit the chemotherapeutic use of DOX. METHODS: This study aimed to evaluate the capability of calcium channel blocker diltiazem (DIL)...

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Detalles Bibliográficos
Autores principales:	Al-malky, Hamdan S., Osman, Abdel-Moneim M., Damanhouri, Zoheir A., Alkreathy, Huda M., Al Aama, Jumana Y., Ramadan, Wafaa S., Al Qahtani, Ali A., Al Mahdi, Hadiah B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657176/ https://www.ncbi.nlm.nih.gov/pubmed/31367189 http://dx.doi.org/10.1186/s12935-019-0912-0

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