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A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival
BACKGROUND: Results of previous studies on the association of the CpG island methylator phenotype (CIMP) with colorectal cancer (CRC) prognosis were inconsistent and mostly based on different CIMP definitions. The current study aimed to comprehensively investigate the associations between DNA methyl...
Autores principales: | Jia, Min, Zhang, Yan, Jansen, Lina, Walter, Viola, Edelmann, Dominic, Gündert, Melanie, Tagscherer, Katrin E., Roth, Wilfried, Bewerunge-Hudler, Melanie, Herpel, Esther, Kloor, Matthias, Ulrich, Alexis, Burwinkel, Barbara, Bläker, Hendrik, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657180/ https://www.ncbi.nlm.nih.gov/pubmed/31340858 http://dx.doi.org/10.1186/s13148-019-0703-4 |
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