Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria

BACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed “radical cure”). Tafenoquine is a single-dose 8-aminoquinoline that has recently been registered for t...

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Detalles Bibliográficos
Autores principales: Lacerda, M.V.G., Llanos-Cuentas, A., Krudsood, S., Lon, C., Saunders, D.L., Mohammed, R., Yilma, D., Batista Pereira, D., Espino, F.E.J., Mia, R.Z., Chuquiyauri, R., Val, F., Casapía, M., Monteiro, W.M., Brito, M.A.M., Costa, M.R.F., Buathong, N., Noedl, H., Diro, E., Getie, S., Wubie, K.M., Abdissa, A., Zeynudin, A., Abebe, C., Tada, M.S., Brand, F., Beck, H.-P., Angus, B., Duparc, S., Kleim, J.-P., Kellam, L.M., Rousell, V.M., Jones, S.W., Hardaker, E., Mohamed, K., Clover, D.D., Fletcher, K., Breton, J.J., Ugwuegbulam, C.O., Green, J.A., Koh, G.C.K.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657226/
https://www.ncbi.nlm.nih.gov/pubmed/30650322
http://dx.doi.org/10.1056/NEJMoa1710775

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