Methylwogonin exerts anticancer effects in A375 human malignant melanoma cells through apoptosis induction, DNA damage, cell invasion inhibition and downregulation of the mTOR/PI3K/Akt signalling pathway

INTRODUCTION: The main purpose of the present research was to study the anticancer effects of methylwogonin in A375 human malignant melanoma cells by evaluating its effects on apoptosis, DNA fragmentation, cancer cell invasion and the mTOR/PI3K/AKT signalling pathway. MATERIAL AND METHODS: Effects o...

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Detalles Bibliográficos
Autores principales: Chen, Jiaorong, Huang, Chunmei, Liu, Fangfang, Xu, Zihui, Li, Li, Huang, Zheng, Zhang, Hongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657243/
https://www.ncbi.nlm.nih.gov/pubmed/31360200
http://dx.doi.org/10.5114/aoms.2018.73711

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