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The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib
Sarcomas are a diverse set of malignancies. For soft tissue sarcomas, the kinase and chaperone inhibitor pazopanib is a standard of care therapeutic. Previously, we demonstrated that HDAC inhibitors enhanced pazopanib lethality against sarcoma and other tumor cell types in vitro and in vivo. The pre...
Autores principales: | Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Dent, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657367/ https://www.ncbi.nlm.nih.gov/pubmed/31380285 http://dx.doi.org/10.3389/fonc.2019.00650 |
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