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Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challenges

Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium tuberculosis, the causative agent of TB, have greatly increased our understanding of this pathogen. Since the first...

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Detalles Bibliográficos
Autores principales:	Cohen, Keira A., Manson, Abigail L., Desjardins, Christopher A., Abeel, Thomas, Earl, Ashlee M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657377/ https://www.ncbi.nlm.nih.gov/pubmed/31345251 http://dx.doi.org/10.1186/s13073-019-0660-8

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