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FOXO3 Is Expressed in Ovarian Tissues and Acts as an Apoptosis Initiator in Granulosa Cells of Chickens
FOXO3, which encodes the transcription factor forkhead box O-3 (FoxO3), is a member of the FOXO subfamily of the forkhead box (FOX) family. FOXO3 can be negatively regulated by its phosphorylation by the PI3K/Akt signaling pathway and ultimately drives apoptosis when activated. In mammalian ovaries,...
Autores principales: | Cui, Can, Han, Shunshun, Yin, Huadong, Luo, Bin, Shen, Xiaoxu, Yang, Fuling, Liu, Zihao, Zhu, Qing, Li, Diyan, Wang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657628/ https://www.ncbi.nlm.nih.gov/pubmed/31380433 http://dx.doi.org/10.1155/2019/6902906 |
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