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Porcine Beta-Defensin 2 Provides Protection Against Bacterial Infection by a Direct Bactericidal Activity and Alleviates Inflammation via Interference With the TLR4/NF-κB Pathway

Porcine beta-defensin 2 (PBD-2) which is a member of the family of antimicrobial peptides, is widely expressed in pig organs with a broad spectrum of bactericidal activities confirmed in vitro. We previously demonstrated that transgenic (TG) pigs overexpressing PBD-2 could resist the infection by th...

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Detalles Bibliográficos
Autores principales:	Huang, Chao, Yang, Xi, Huang, Jing, Liu, Xiao, Yang, Xiaoyu, Jin, Hui, Huang, Qi, Li, Lu, Zhou, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657668/ https://www.ncbi.nlm.nih.gov/pubmed/31379864 http://dx.doi.org/10.3389/fimmu.2019.01673

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