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Aneuploidy Enables Cross-Adaptation to Unrelated Drugs

Aneuploidy is common both in tumor cells responding to chemotherapeutic agents and in fungal cells adapting to antifungal drugs. Because aneuploidy simultaneously affects many genes, it has the potential to confer multiple phenotypes to the same cells. Here, we analyzed the mechanisms by which Candi...

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Detalles Bibliográficos
Autores principales: Yang, Feng, Teoh, Flora, Tan, Alrina Shin Min, Cao, Yongbing, Pavelka, Norman, Berman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657732/
https://www.ncbi.nlm.nih.gov/pubmed/31028698
http://dx.doi.org/10.1093/molbev/msz104