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Conditioned medium of primary lung cancer cells induces EMT in A549 lung cancer cell line by TGF-ß1 and miRNA21 cooperation

The epithelial-mesenchymal transition (EMT) plays a key role in tumor progression, drug resistance and metastasis. Recently, numerous microRNA (miRNA) have been described to regulate EMT in tumor progression. In this study, we found that conditioned medium from the LC212 non-small-cell lung cancer (...

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Detalles Bibliográficos
Autores principales: Camerlingo, Rosa, Miceli, Roberta, Marra, Laura, Rea, Giuseppina, D’Agnano, Igea, Nardella, Marta, Montella, Roberta, Morabito, Alessandro, Normanno, Nicola, Tirino, Virginia, Rocco, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657837/
https://www.ncbi.nlm.nih.gov/pubmed/31344049
http://dx.doi.org/10.1371/journal.pone.0219597

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