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Conditioned medium of primary lung cancer cells induces EMT in A549 lung cancer cell line by TGF-ß1 and miRNA21 cooperation
The epithelial-mesenchymal transition (EMT) plays a key role in tumor progression, drug resistance and metastasis. Recently, numerous microRNA (miRNA) have been described to regulate EMT in tumor progression. In this study, we found that conditioned medium from the LC212 non-small-cell lung cancer (...
Autores principales: | Camerlingo, Rosa, Miceli, Roberta, Marra, Laura, Rea, Giuseppina, D’Agnano, Igea, Nardella, Marta, Montella, Roberta, Morabito, Alessandro, Normanno, Nicola, Tirino, Virginia, Rocco, Gaetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657837/ https://www.ncbi.nlm.nih.gov/pubmed/31344049 http://dx.doi.org/10.1371/journal.pone.0219597 |
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