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SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation

Hepatitis C virus (HCV) replication involves many viral and host factors. Host factor SPRY domain- and SOCS box-containing protein 2(SPSB2) belongs to SPSB family, and it recruits target proteins by the SPRY domain and forms E3 ubiquitin ligase complexes by the SOCS box. As an adaptor protein, it ca...

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Detalles Bibliográficos
Autores principales:	Wang, Mingzhen, Wang, Yu, Liu, Yuehong, Wang, Hailong, Xin, Xiu, Li, Jiadai, Hao, Yao, Han, Lingling, Yu, Fang, Zheng, Congyi, Shen, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657855/ https://www.ncbi.nlm.nih.gov/pubmed/31344133 http://dx.doi.org/10.1371/journal.pone.0219989

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