Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge

Pemphigus vulgaris (PV) is an autoimmune blistering disorder of skin and mucous membranes, characterized by acantholysis, can be life threatening, and carries significant morbidity. Esophageal involvement is uncommon, and the diagnosis can often be delayed. Esophageal stricture secondary to PV is ex...

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Autores principales: Usman, Rana Muhammad, Jehangir, Qasim, Bilal, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657999/
https://www.ncbi.nlm.nih.gov/pubmed/31616720
http://dx.doi.org/10.14309/crj.0000000000000022
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author Usman, Rana Muhammad
Jehangir, Qasim
Bilal, Muhammad
author_facet Usman, Rana Muhammad
Jehangir, Qasim
Bilal, Muhammad
author_sort Usman, Rana Muhammad
collection PubMed
description Pemphigus vulgaris (PV) is an autoimmune blistering disorder of skin and mucous membranes, characterized by acantholysis, can be life threatening, and carries significant morbidity. Esophageal involvement is uncommon, and the diagnosis can often be delayed. Esophageal stricture secondary to PV is extremely rare, and there are no guidelines on the management of this complication. We present a case of recalcitrant esophageal stricture, secondary to PV, successfully treated with topical and intralesional steroids. Moreover, we review the literature pertaining to esophageal PV and the management of esophageal strictures.
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spelling pubmed-66579992019-10-15 Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge Usman, Rana Muhammad Jehangir, Qasim Bilal, Muhammad ACG Case Rep J Case Report Pemphigus vulgaris (PV) is an autoimmune blistering disorder of skin and mucous membranes, characterized by acantholysis, can be life threatening, and carries significant morbidity. Esophageal involvement is uncommon, and the diagnosis can often be delayed. Esophageal stricture secondary to PV is extremely rare, and there are no guidelines on the management of this complication. We present a case of recalcitrant esophageal stricture, secondary to PV, successfully treated with topical and intralesional steroids. Moreover, we review the literature pertaining to esophageal PV and the management of esophageal strictures. Wolters Kluwer 2019-02-25 /pmc/articles/PMC6657999/ /pubmed/31616720 http://dx.doi.org/10.14309/crj.0000000000000022 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Usman, Rana Muhammad
Jehangir, Qasim
Bilal, Muhammad
Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge
title Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge
title_full Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge
title_fullStr Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge
title_full_unstemmed Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge
title_short Recurrent Esophageal Stricture Secondary to Pemphigus Vulgaris: A Rare Diagnostic and Therapeutic Challenge
title_sort recurrent esophageal stricture secondary to pemphigus vulgaris: a rare diagnostic and therapeutic challenge
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657999/
https://www.ncbi.nlm.nih.gov/pubmed/31616720
http://dx.doi.org/10.14309/crj.0000000000000022
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AT jehangirqasim recurrentesophagealstricturesecondarytopemphigusvulgarisararediagnosticandtherapeuticchallenge
AT bilalmuhammad recurrentesophagealstricturesecondarytopemphigusvulgarisararediagnosticandtherapeuticchallenge

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