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Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis

BACKGROUND: Glanders caused by Burkholderia mallei is a re-emerging zoonotic disease affecting solipeds and humans. Furthermore, B. mallei is genetically related to B. pseudomallei, which is the causative agent of melioidosis. Both facultative intracellular bacteria are classified as tier 1 select b...

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Detalles Bibliográficos
Autores principales:	Khakhum, Nittaya, Bharaj, Preeti, Myers, Julia N., Tapia, Daniel, Walker, David H., Endsley, Janice J., Torres, Alfredo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658008/ https://www.ncbi.nlm.nih.gov/pubmed/31306423 http://dx.doi.org/10.1371/journal.pntd.0007578

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