Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Alzheimer’s disease (AD) is a leading cause of mortality in the elderly. While the coding change of APOE-ε4 is a key risk factor for late-onset AD and has been believed to be the only risk factor in the APOE locus, it does not fully explain the risk effect conferred by the locus. Here, we report the...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Kwok, Timothy C. Y., Mok, Vincent C. T., Guo, Qihao, Ip, Fanny C., Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F., Hardy, John, Fu, Amy K. Y., Li, Yun, Ip, Nancy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658518/
https://www.ncbi.nlm.nih.gov/pubmed/31346172
http://dx.doi.org/10.1038/s41467-019-10945-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658518/
https://www.ncbi.nlm.nih.gov/pubmed/31346172
http://dx.doi.org/10.1038/s41467-019-10945-z

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