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Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model
Transplantation of cardiomyocytes derived from induced pluripotent stem cell (iPSC-CMs) is a promising approach for increasing functional CMs during end-stage heart failure. Although major histocompatibility complex (MHC) class I matching between donor cells and recipient could reduce acquired immun...
Autores principales: | Nakamura, Yuki, Miyagawa, Shigeru, Yoshida, Shohei, Sasawatari, Shigemi, Toyofuku, Toshihiko, Toda, Koichi, Sawa, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658523/ https://www.ncbi.nlm.nih.gov/pubmed/31346220 http://dx.doi.org/10.1038/s41598-019-47134-3 |
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