Neuronal XBP-1 Activates Intestinal Lysosomes to Improve Proteostasis in C. elegans

The unfolded protein response of the endoplasmic reticulum (UPR(ER)) is a crucial mediator of secretory pathway homeostasis. Expression of the spliced and active form of the UPR(ER) transcription factor XBP-1, XBP-1s, in the nervous system triggers activation of the UPR(ER) in the intestine of Caeno...

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Detalles Bibliográficos
Autores principales: Imanikia, Soudabeh, Özbey, Neşem P., Krueger, Christel, Casanueva, M. Olivia, Taylor, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658570/
https://www.ncbi.nlm.nih.gov/pubmed/31303493
http://dx.doi.org/10.1016/j.cub.2019.06.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658570/
https://www.ncbi.nlm.nih.gov/pubmed/31303493
http://dx.doi.org/10.1016/j.cub.2019.06.031

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