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Depletion of Hemoglobin Transcripts and Long-Read Sequencing Improves the Transcriptome Annotation of the Polar Bear (Ursus maritimus)

Transcriptome studies evaluating whole blood and tissues are often confounded by overrepresentation of highly abundant transcripts. These abundant transcripts are problematic, as they compete with and prevent the detection of rare RNA transcripts, obscuring their biological importance. This issue is...

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Detalles Bibliográficos
Autores principales: Byrne, Ashley, Supple, Megan A., Volden, Roger, Laidre, Kristin L., Shapiro, Beth, Vollmers, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658610/
https://www.ncbi.nlm.nih.gov/pubmed/31379921
http://dx.doi.org/10.3389/fgene.2019.00643