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Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients
The number of Left Ventricular Assist Devices (LVADs) implanted each year is rising. Nevertheless, there are minimal data on device acceptance after LVAD implant, and on its relationship with patient-reported outcomes. We designed a cross-sectional study to address this knowledge gap and test the hy...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658659/ https://www.ncbi.nlm.nih.gov/pubmed/31346241 http://dx.doi.org/10.1038/s41598-019-47324-z |
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author | Tosto, Crispino Adamo, Luigi Craddock, Heidi Di Blasi, Maria Girgenti, Rosario Clemenza, Francesco Carney, Robert M. Ewald, Gregory |
author_facet | Tosto, Crispino Adamo, Luigi Craddock, Heidi Di Blasi, Maria Girgenti, Rosario Clemenza, Francesco Carney, Robert M. Ewald, Gregory |
author_sort | Tosto, Crispino |
collection | PubMed |
description | The number of Left Ventricular Assist Devices (LVADs) implanted each year is rising. Nevertheless, there are minimal data on device acceptance after LVAD implant, and on its relationship with patient-reported outcomes. We designed a cross-sectional study to address this knowledge gap and test the hypothesis that low device acceptance is associated with poorer quality of life, depression and anxiety. Self-report questionnaires were administered to assess quality of life (12-item Kansas City Cardiomyopathy Questionnaire quality of life subscale), level of anxiety (7-item Generalized Anxiety Disorder; GAD-7), level of depression (9-item Patient Health Questionnaire; PHQ-9) and device acceptance (Florida Patient Acceptance Survey; FPAS) to 101 consecutive patients presenting to LVAD clinic. Regression analysis showed a strong correlation between device acceptance and both psychological distress (p < 0.001) and quality of life (p < 0.001). Analysis of the sub-scales of the FPAS showed that patients had significant body image concerns, but return to function and device-related distress were the main drivers of the observed correlation between device acceptance and patient well-being. Younger age was associated with lower device acceptance (r = 0.36, p < 0.001) and lower quality of life (r = 0.54, p < 0.001). These findings suggest that interventions targeting device acceptance should be explored to improve outcomes in LVAD recipients. |
format | Online Article Text |
id | pubmed-6658659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-66586592019-07-31 Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients Tosto, Crispino Adamo, Luigi Craddock, Heidi Di Blasi, Maria Girgenti, Rosario Clemenza, Francesco Carney, Robert M. Ewald, Gregory Sci Rep Article The number of Left Ventricular Assist Devices (LVADs) implanted each year is rising. Nevertheless, there are minimal data on device acceptance after LVAD implant, and on its relationship with patient-reported outcomes. We designed a cross-sectional study to address this knowledge gap and test the hypothesis that low device acceptance is associated with poorer quality of life, depression and anxiety. Self-report questionnaires were administered to assess quality of life (12-item Kansas City Cardiomyopathy Questionnaire quality of life subscale), level of anxiety (7-item Generalized Anxiety Disorder; GAD-7), level of depression (9-item Patient Health Questionnaire; PHQ-9) and device acceptance (Florida Patient Acceptance Survey; FPAS) to 101 consecutive patients presenting to LVAD clinic. Regression analysis showed a strong correlation between device acceptance and both psychological distress (p < 0.001) and quality of life (p < 0.001). Analysis of the sub-scales of the FPAS showed that patients had significant body image concerns, but return to function and device-related distress were the main drivers of the observed correlation between device acceptance and patient well-being. Younger age was associated with lower device acceptance (r = 0.36, p < 0.001) and lower quality of life (r = 0.54, p < 0.001). These findings suggest that interventions targeting device acceptance should be explored to improve outcomes in LVAD recipients. Nature Publishing Group UK 2019-07-25 /pmc/articles/PMC6658659/ /pubmed/31346241 http://dx.doi.org/10.1038/s41598-019-47324-z Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Tosto, Crispino Adamo, Luigi Craddock, Heidi Di Blasi, Maria Girgenti, Rosario Clemenza, Francesco Carney, Robert M. Ewald, Gregory Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients |
title | Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients |
title_full | Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients |
title_fullStr | Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients |
title_full_unstemmed | Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients |
title_short | Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients |
title_sort | relationship between device acceptance and patient-reported outcomes in left ventricular assist device (lvad) recipients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658659/ https://www.ncbi.nlm.nih.gov/pubmed/31346241 http://dx.doi.org/10.1038/s41598-019-47324-z |
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