Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei

The arsenal of drugs used to treat leishmaniasis, caused by Leishmania spp., is limited and beset by toxicity and emergent resistance. Furthermore, our understanding of drug mode of action and potential routes to resistance is limited. Forward genetic approaches have revolutionized our understanding...

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Detalles Bibliográficos
Autores principales: Collett, Clare F., Kitson, Carl, Baker, Nicola, Steele-Stallard, Heather B., Santrot, Marie-Victoire, Hutchinson, Sebastian, Horn, David, Alsford, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658743/
https://www.ncbi.nlm.nih.gov/pubmed/31160283
http://dx.doi.org/10.1128/AAC.00795-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658743/
https://www.ncbi.nlm.nih.gov/pubmed/31160283
http://dx.doi.org/10.1128/AAC.00795-19

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