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Evaluation of a Library of FDA-Approved Drugs for Their Ability To Potentiate Antibiotics against Multidrug-Resistant Gram-Negative Pathogens

The Prestwick library was screened for antibacterial activity or “antibiotic resistance breaker” (ARB) potential against four species of Gram-negative pathogens. Discounting known antibacterials, the screen identified very few ARB hits, which were strain/drug specific. These ARB hits included antime...

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Detalles Bibliográficos
Autores principales:	Hind, Charlotte K., Dowson, Christopher G., Sutton, J. Mark, Jackson, Thomas, Clifford, Melanie, Garner, R. Colin, Czaplewski, Lloyd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658780/ https://www.ncbi.nlm.nih.gov/pubmed/31160293 http://dx.doi.org/10.1128/AAC.00769-19

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