Cargando…

Emergence of Oxacillin Resistance in Stealth Methicillin-Resistant Staphylococcus aureus Due to mecA Sequence Instability

Staphylococcus aureus strains that possess a mecA gene but are phenotypically susceptible to oxacillin and cefoxitin (OS-MRSA) have been recognized for over a decade and are a challenge for diagnostic laboratories. The mechanisms underlying the discrepancy vary from isolate to isolate. We characteri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goering, Richard V., Swartzendruber, Erin A., Obradovich, Anne E., Tickler, Isabella A., Tenover, Fred C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658785/ https://www.ncbi.nlm.nih.gov/pubmed/31109981 http://dx.doi.org/10.1128/AAC.00558-19

Ejemplares similares

Characterization of SCCmec Instability in Methicillin-Resistant Staphylococcus aureus Affecting Adjacent Chromosomal Regions, Including the Gene for Staphylococcal Protein A (spa)
por: Scharn, C. R., et al.
Publicado: (2022)

First Report of cfr-Carrying Plasmids in the Pandemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Staphylococcal Cassette Chromosome mec Type IV Clone
por: Shore, Anna C., et al.
Publicado: (2016)

Prevalence of Slow-Growth Vancomycin Nonsusceptibility in Methicillin-Resistant Staphylococcus aureus
por: Katayama, Yuki, et al.
Publicado: (2017)

The Sle1 Cell Wall Amidase Is Essential for β-Lactam Resistance in Community-Acquired Methicillin-Resistant Staphylococcus aureus USA300
por: Thalsø-Madsen, Ida, et al.
Publicado: (2019)

SNP Scanning in mecA Gene for Methicillin-Resistant Staphylococcus aureus
por: Salehi, Mitra, et al.
Publicado: (2020)

Remodeling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in a Dominant Hospital Lineage of Methicillin-Resistant Staphylococcus aureus
por: Baines, Sarah L., et al.
Publicado: (2019)

Identification and characterization of mutations responsible for the β-lactam resistance in oxacillin-susceptible mecA-positive Staphylococcus aureus
por: Boonsiri, Tanit, et al.
Publicado: (2020)

Genomic Basis of Occurrence of Cryptic Resistance among Oxacillin- and Cefoxitin-Susceptible mecA-Positive Staphylococcus aureus
por: Liang, Bingshao, et al.
Publicado: (2022)

Repeated Emergence of Variant TetR Family Regulator, FarR, and Increased Resistance to Antimicrobial Unsaturated Fatty Acid among Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus
por: Bonn, Camryn M., et al.
Publicado: (2023)

Detection of Methicillin-Resistant Staphylococcus aureus Infections Using Molecular Methods
por: Tenover, Fred C., et al.
Publicado: (2022)

Updating Molecular Diagnostics for Detecting Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Isolates in Blood Culture Bottles
por: Tenover, Fred C., et al.
Publicado: (2019)

Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline
por: Larsen, Jesper, et al.
Publicado: (2016)

Antibiotics Limit Adaptation of Drug-Resistant Staphylococcus aureus to Hypoxia
por: Hull, Rebecca C., et al.
Publicado: (2022)

Prevalence of mecA- and mecC-Associated Methicillin-Resistant Staphylococcus aureus in Clinical Specimens, Punjab, Pakistan
por: Idrees, Muhammad Mubashar, et al.
Publicado: (2023)

Impact of the Stringent Stress Response on the Expression of Methicillin Resistance in Staphylococcaceae Strains Carrying mecA, mecA1 and mecC
por: Milheiriço, Catarina, et al.
Publicado: (2022)

In vitro transfer of methicillin resistance determinants mecA from methicillin resistant Staphylococcus aureus (MRSA) to methicillin susceptible Staphylococcus aureus (MSSA)
por: Bitrus, Asinamai Athliamai, et al.
Publicado: (2017)

First Report of Oxacillin Susceptible mecA-Positive Staphylococcus aureus in a Children’s Hospital in Kunming, China
por: Ma, Mingbiao, et al.
Publicado: (2021)

Clinical Relevance of Topical Antibiotic Use in Coselecting for Multidrug-Resistant Staphylococcus aureus: Insights from In Vitro and Ex Vivo Models
por: Nong, Yi, et al.
Publicado: (2021)

Identification and Characterization of a Novel Major Facilitator Superfamily Efflux Pump, SA09310, Mediating Tetracycline Resistance in Staphylococcus aureus
por: Li, Daiyu, et al.
Publicado: (2023)

Modulation of mecA Gene Expression by Essential Oil from Salvia sclarea and Synergism with Oxacillin in Methicillin Resistant Staphylococcus epidermidis Carrying Different Types of Staphylococcal Chromosomal Cassette mec
por: Chovanová, Romana, et al.
Publicado: (2016)

High Incidence of Oxacillin-Susceptible mecA-Positive Staphylococcus aureus (OS-MRSA) Associated with Bovine Mastitis in China
por: Pu, WanXia, et al.
Publicado: (2014)

Prevalence and Characterization of Oxacillin Susceptible mecA-Positive Clinical Isolates of Staphylococcus aureus Causing Bovine Mastitis in India
por: Mistry, Hiral, et al.
Publicado: (2016)

Potential of Tetracycline Resistance Proteins To Evolve Tigecycline Resistance
por: Linkevicius, Marius, et al.
Publicado: (2016)

What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis
por: Heyckendorf, Jan, et al.
Publicado: (2018)

Predicting Antibiotic Resistance in Gram-Negative Bacilli from Resistance Genes
por: Walker, G. Terrance, et al.
Publicado: (2019)

Complete Reconstitution of the Vancomycin-Intermediate Staphylococcus aureus Phenotype of Strain Mu50 in Vancomycin-Susceptible S. aureus
por: Katayama, Yuki, et al.
Publicado: (2016)

Correction: Prevalence and Characterization of Oxacillin Susceptible mecA-Positive Clinical Isolates of Staphylococcus aureus Causing Bovine Mastitis in India
por: Mistry, Hiral, et al.
Publicado: (2020)

Methicillin-Resistance in Staphylococcus aureus Is Not Affected by the Overexpression in Trans of the mecA Gene Repressor: A Surprising Observation
por: Oliveira, Duarte C., et al.
Publicado: (2011)

Epidemiology of mecA-Methicillin Resistant Staphylococcus aureus (MRSA) in Iran: A Systematic Review and Meta-analysis
por: Askari, Emran, et al.
Publicado: (2012)

The NaHCO(3)-Responsive Phenotype in Methicillin-Resistant Staphylococcus aureus (MRSA) Is Influenced by mecA Genotype
por: Ersoy, Selvi C., et al.
Publicado: (2022)

Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae
por: Sun, Dongxu, et al.
Publicado: (2017)

Comprehensive Genome Analysis of Carbapenem-Resistant Strains of Raoultella Species, an Emerging Multidrug-Resistant Bacterium in Hospitals
por: Yu, Xiao, et al.
Publicado: (2019)

Inducible Resistance to β-Lactams in Oxacillin-Susceptible mecA1-Positive Staphylococcus sciuri Isolated From Retail Pork
por: Cai, Yifei, et al.
Publicado: (2021)

Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates
por: Karah, Nabil, et al.
Publicado: (2016)

Isoniazid Resistance in Mycobacterium tuberculosis Is a Heterogeneous Phenotype Composed of Overlapping MIC Distributions with Different Underlying Resistance Mechanisms
por: Ghodousi, Arash, et al.
Publicado: (2019)

First mecC and mecA Positive Livestock-Associated Methicillin Resistant Staphylococcus aureus (mecC MRSA/LA-MRSA) from Dairy Cattle in Malaysia
por: Aklilu, Erkihun, et al.
Publicado: (2020)

Antimicrobial Resistance, Biofilm Formation and mecA Characterization of Methicillin-Susceptible S. aureus and Non-S. aureus of Beef Meat Origin in Egypt
por: Osman, Kamelia M., et al.
Publicado: (2016)

Evolution of Antibiotic Resistance without Antibiotic Exposure
por: Knöppel, Anna, et al.
Publicado: (2017)

Azole Resistance Mechanisms in Pathogenic Malassezia furfur
por: Leong, Cheryl, et al.
Publicado: (2021)

Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus
por: Khateb, Aiah, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_604tovt09vbi3hvu5j64plkm5m