The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo

In 2012, a carbapenemase-producing Salmonella enterica serovar Corvallis isolate carrying a bla(NDM-1) multiresistance IncA/C(2) plasmid, apart from IncHI2 and ColE-like plasmids, was detected in a wild bird in Germany. In a recent broiler chicken infection study, we observed transfer of this bla(ND...

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Autores principales: Hadziabdic, Sead, Fischer, Jennie, Borowiak, Maria, Malorny, Burkhard, Juraschek, Katharina, Kaesbohrer, Annemarie, Guerra, Beatriz, Deneke, Carlus, Gonzalez-Zorn, Bruno, Szabo, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658791/
https://www.ncbi.nlm.nih.gov/pubmed/31109975
http://dx.doi.org/10.1128/AAC.00380-19
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author Hadziabdic, Sead
Fischer, Jennie
Borowiak, Maria
Malorny, Burkhard
Juraschek, Katharina
Kaesbohrer, Annemarie
Guerra, Beatriz
Deneke, Carlus
Gonzalez-Zorn, Bruno
Szabo, Istvan
author_facet Hadziabdic, Sead
Fischer, Jennie
Borowiak, Maria
Malorny, Burkhard
Juraschek, Katharina
Kaesbohrer, Annemarie
Guerra, Beatriz
Deneke, Carlus
Gonzalez-Zorn, Bruno
Szabo, Istvan
author_sort Hadziabdic, Sead
collection PubMed
description In 2012, a carbapenemase-producing Salmonella enterica serovar Corvallis isolate carrying a bla(NDM-1) multiresistance IncA/C(2) plasmid, apart from IncHI2 and ColE-like plasmids, was detected in a wild bird in Germany. In a recent broiler chicken infection study, we observed transfer of this bla(NDM-1)-carrying IncA/C(2) plasmid to other Enterobacteriaceae. Here, we focused on the stability of this plasmid and gained insight into the type and frequency of its structural alterations after an in vivo passage in a broiler chicken infection study.
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spelling pubmed-66587912019-08-07 The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo Hadziabdic, Sead Fischer, Jennie Borowiak, Maria Malorny, Burkhard Juraschek, Katharina Kaesbohrer, Annemarie Guerra, Beatriz Deneke, Carlus Gonzalez-Zorn, Bruno Szabo, Istvan Antimicrob Agents Chemother Mechanisms of Resistance In 2012, a carbapenemase-producing Salmonella enterica serovar Corvallis isolate carrying a bla(NDM-1) multiresistance IncA/C(2) plasmid, apart from IncHI2 and ColE-like plasmids, was detected in a wild bird in Germany. In a recent broiler chicken infection study, we observed transfer of this bla(NDM-1)-carrying IncA/C(2) plasmid to other Enterobacteriaceae. Here, we focused on the stability of this plasmid and gained insight into the type and frequency of its structural alterations after an in vivo passage in a broiler chicken infection study. American Society for Microbiology 2019-07-25 /pmc/articles/PMC6658791/ /pubmed/31109975 http://dx.doi.org/10.1128/AAC.00380-19 Text en Copyright © 2019 Hadziabdic et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Mechanisms of Resistance
Hadziabdic, Sead
Fischer, Jennie
Borowiak, Maria
Malorny, Burkhard
Juraschek, Katharina
Kaesbohrer, Annemarie
Guerra, Beatriz
Deneke, Carlus
Gonzalez-Zorn, Bruno
Szabo, Istvan
The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo
title The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo
title_full The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo
title_fullStr The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo
title_full_unstemmed The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo
title_short The bla(NDM-1)-Carrying IncA/C(2) Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo
title_sort bla(ndm-1)-carrying inca/c(2) plasmid underlies structural alterations and cointegrate formation in vivo
topic Mechanisms of Resistance
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658791/
https://www.ncbi.nlm.nih.gov/pubmed/31109975
http://dx.doi.org/10.1128/AAC.00380-19
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