Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response

OBJECTIVES: PD-L1 expression on tumour cells can guide the use of anti-PD-1/PD-L1 immune modulators to treat patients with non-small cell lung cancer (NSCLC). Heterogeneity of PD-L1 expression both within and between tumour sites is a well-documented phenomenon that compromises its predictive power....

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Detalles Bibliográficos
Autores principales: Haragan, Alexander, Field, John K., Davies, Michael P.A., Escriu, Carles, Gruver, Aaron, Gosney, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658831/
https://www.ncbi.nlm.nih.gov/pubmed/31320000
http://dx.doi.org/10.1016/j.lungcan.2019.06.005

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