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Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy
OBJECTIVE: To evaluate the effectiveness of three different caries-preventing agents on artificial caries in a Streptococcus mutans-based caries model. METHODS: Sixty-five caries-free human molar enamel blocks were treated with a demineralization solution and a remineralization solution. The specime...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association of Orthodontists
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658901/ https://www.ncbi.nlm.nih.gov/pubmed/31367579 http://dx.doi.org/10.4041/kjod.2019.49.4.246 |
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author | Park, Kyung-Jin Kroker, Tessa Groß, Uwe Zimmermann, Ortrud Krause, Felix Haak, Rainer Ziebolz, Dirk |
author_facet | Park, Kyung-Jin Kroker, Tessa Groß, Uwe Zimmermann, Ortrud Krause, Felix Haak, Rainer Ziebolz, Dirk |
author_sort | Park, Kyung-Jin |
collection | PubMed |
description | OBJECTIVE: To evaluate the effectiveness of three different caries-preventing agents on artificial caries in a Streptococcus mutans-based caries model. METHODS: Sixty-five caries-free human molar enamel blocks were treated with a demineralization solution and a remineralization solution. The specimens were assigned to the following groups according to the caries-protective product applied: group A, chlorhexidine varnish; group B, fluoride-releasing chemically cured sealant; group C, fluoride-releasing lightcured sealant; group D, positive control (specimens that were subjected to de- and remineralization cycles without treatment with any caries-protective agents); and group E, negative control (specimens that were not subjected to de- and remineralization cycles). Samples in groups A–D were stored in demineralization solution with S. mutans and thereafter in artificial saliva. This procedure was performed for 30 days. Average fluorescence loss (ΔF) and surface size of the lesions were measured using quantitative light-induced fluorescence at baseline and on the 7th, 14th, and 30th days. RESULTS: After 30 days, group A demonstrated a significant increase in ΔF and the surface size of the lesions, no significant difference in comparison with the positive control group, and a significant difference in comparison with the negative control group. Group B showed no significant changes in both parameters at any of the measurement points. While group C showed increased ΔF after 14 days, no significant fluorescence change was observed after 30 days. CONCLUSIONS: Both fluoride-releasing sealants (chemically or light-cured) show anti-cariogenic effects, but the use of chlorhexidine varnish for the purpose of caries protection needs to be reconsidered. |
format | Online Article Text |
id | pubmed-6658901 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Association of Orthodontists |
record_format | MEDLINE/PubMed |
spelling | pubmed-66589012019-07-31 Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy Park, Kyung-Jin Kroker, Tessa Groß, Uwe Zimmermann, Ortrud Krause, Felix Haak, Rainer Ziebolz, Dirk Korean J Orthod Original Article OBJECTIVE: To evaluate the effectiveness of three different caries-preventing agents on artificial caries in a Streptococcus mutans-based caries model. METHODS: Sixty-five caries-free human molar enamel blocks were treated with a demineralization solution and a remineralization solution. The specimens were assigned to the following groups according to the caries-protective product applied: group A, chlorhexidine varnish; group B, fluoride-releasing chemically cured sealant; group C, fluoride-releasing lightcured sealant; group D, positive control (specimens that were subjected to de- and remineralization cycles without treatment with any caries-protective agents); and group E, negative control (specimens that were not subjected to de- and remineralization cycles). Samples in groups A–D were stored in demineralization solution with S. mutans and thereafter in artificial saliva. This procedure was performed for 30 days. Average fluorescence loss (ΔF) and surface size of the lesions were measured using quantitative light-induced fluorescence at baseline and on the 7th, 14th, and 30th days. RESULTS: After 30 days, group A demonstrated a significant increase in ΔF and the surface size of the lesions, no significant difference in comparison with the positive control group, and a significant difference in comparison with the negative control group. Group B showed no significant changes in both parameters at any of the measurement points. While group C showed increased ΔF after 14 days, no significant fluorescence change was observed after 30 days. CONCLUSIONS: Both fluoride-releasing sealants (chemically or light-cured) show anti-cariogenic effects, but the use of chlorhexidine varnish for the purpose of caries protection needs to be reconsidered. Korean Association of Orthodontists 2019-07 2019-07-22 /pmc/articles/PMC6658901/ /pubmed/31367579 http://dx.doi.org/10.4041/kjod.2019.49.4.246 Text en © 2019 The Korean Association of Orthodontists. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Kyung-Jin Kroker, Tessa Groß, Uwe Zimmermann, Ortrud Krause, Felix Haak, Rainer Ziebolz, Dirk Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
title | Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
title_full | Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
title_fullStr | Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
title_full_unstemmed | Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
title_short | Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
title_sort | effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658901/ https://www.ncbi.nlm.nih.gov/pubmed/31367579 http://dx.doi.org/10.4041/kjod.2019.49.4.246 |
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