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The role of CXCR4 in multiple myeloma: Cells’ journey from bone marrow to beyond
CXCR4 is a pleiotropic chemokine receptor which acts through its ligand CXCL12 to regulate diverse physiological processes. CXCR4/CXCL12 axis plays a pivotal role in proliferation, invasion, dissemination and drug resistance in multiple myeloma (MM). Apart from its role in homing, CXCR4 also affects...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658931/ https://www.ncbi.nlm.nih.gov/pubmed/31372333 http://dx.doi.org/10.1016/j.jbo.2019.100253 |