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Pharmacological characterization of the seven human NOX isoforms and their inhibitors
BACKGROUND: NADPH oxidases (NOX) are a family of flavoenzymes that catalyze the formation of superoxide anion radical (O(2)(•-)) and/or hydrogen peroxide (H(2)O(2)). As major oxidant generators, NOX are associated with oxidative damage in numerous diseases and represent promising drug targets for se...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658998/ https://www.ncbi.nlm.nih.gov/pubmed/31330481 http://dx.doi.org/10.1016/j.redox.2019.101272 |