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T Cell Dysfunction in Cancer Immunity and Immunotherapy

In cancer, T cells become dysfunctional owing to persistent antigen exposure. Dysfunctional T cells are characterized by reduced proliferative capacity, decreased effector function, and overexpression of multiple inhibitory receptors. Due to the presence of various inhibitory signals in the complex...

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Detalles Bibliográficos
Autores principales:	Xia, Anliang, Zhang, Yan, Xu, Jiang, Yin, Tailang, Lu, Xiao-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659036/ https://www.ncbi.nlm.nih.gov/pubmed/31379886 http://dx.doi.org/10.3389/fimmu.2019.01719

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