Cargando…
Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease
Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the genome, complicating the genetic and genomic studies of these highly repetitive sequences. The recent devel...
Autores principales: | Tam, Oliver H., Ostrow, Lyle W., Gale Hammell, Molly |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659213/ https://www.ncbi.nlm.nih.gov/pubmed/31372185 http://dx.doi.org/10.1186/s13100-019-0176-1 |
Ejemplares similares
-
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
por: Tam, Oliver H., et al.
Publicado: (2019) -
Editorial Overview: Endogenous Retroviruses in Development and Disease
por: Gale Hammell, Molly, et al.
Publicado: (2020) -
Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System
por: Bae, Mihyeon, et al.
Publicado: (2020) -
Ten simple rules for running a successful women-in-STEM organization on an academic campus
por: Rupert, Deborah D., et al.
Publicado: (2020) -
Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS
por: Krug, Lisa, et al.
Publicado: (2017)