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miR-449a regulates insulin signalling by targeting the Notch ligand, Jag1 in skeletal muscle cells
BACKGROUND: miR-449a, an intronic miRNA, is highly down-regulated in the skeletal muscle during diabetes. Its levels are epigenetically regulated by altered acetylation/deacetylation on the promoter that it shares with its host gene, Cdc20b. However, the cellular role of this epigenetically regulate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659245/ https://www.ncbi.nlm.nih.gov/pubmed/31345231 http://dx.doi.org/10.1186/s12964-019-0394-7 |