Dietary curcumin enhances insulin clearance in diet-induced obese mice via regulation of hepatic PI3K-AKT axis and IDE, and preservation of islet integrity

BACKGROUND: Although type 2 diabetes mellitus (T2DM) is primarily characterized by sustained high levels of circulating glucose, other factors, such as obesity, chronic inflammation, fatty liver, and islet dysfunction significantly contribute to the development of this disease. To date, curcumin (CU...

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Detalles Bibliográficos
Autores principales: Kim, Yoo, Rouse, Michael, González-Mariscal, Isabel, Egan, Josephine M., O’Connell, Jennifer F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659288/
https://www.ncbi.nlm.nih.gov/pubmed/31372175
http://dx.doi.org/10.1186/s12986-019-0377-0

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