Induction of labor and postpartum blood loss

BACKGROUND: To analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor. METHODS: In this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction...

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Autores principales: Brun, Romana, Spoerri, Emilian, Schäffer, Leonhard, Zimmermann, Roland, Haslinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659310/
https://www.ncbi.nlm.nih.gov/pubmed/31345178
http://dx.doi.org/10.1186/s12884-019-2410-8
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author Brun, Romana
Spoerri, Emilian
Schäffer, Leonhard
Zimmermann, Roland
Haslinger, Christian
author_facet Brun, Romana
Spoerri, Emilian
Schäffer, Leonhard
Zimmermann, Roland
Haslinger, Christian
author_sort Brun, Romana
collection PubMed
description BACKGROUND: To analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor. METHODS: In this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction of labor (39%) between 2015 and 2016. Primary outcome parameters were rate of postpartum hemorrhage, estimated blood loss and post-partum decrease in hemoglobin. RESULTS: Rates of postpartum hemorrhage and estimated blood loss were not significantly different in women with induction of labor. Women with induction of labor had a significantly reduced decrease in hemoglobin after delivery. In the multivariate linear regression analysis, induction of labor remained associated with reduced decrease in hemoglobin. Secondary maternal and neonatal outcomes were unaffected. CONCLUSIONS: Induction of labor is not associated with increased blood loss after delivery and should not be regarded as a risk factor for postpartum hemorrhage.
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spelling pubmed-66593102019-08-01 Induction of labor and postpartum blood loss Brun, Romana Spoerri, Emilian Schäffer, Leonhard Zimmermann, Roland Haslinger, Christian BMC Pregnancy Childbirth Research Article BACKGROUND: To analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor. METHODS: In this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction of labor (39%) between 2015 and 2016. Primary outcome parameters were rate of postpartum hemorrhage, estimated blood loss and post-partum decrease in hemoglobin. RESULTS: Rates of postpartum hemorrhage and estimated blood loss were not significantly different in women with induction of labor. Women with induction of labor had a significantly reduced decrease in hemoglobin after delivery. In the multivariate linear regression analysis, induction of labor remained associated with reduced decrease in hemoglobin. Secondary maternal and neonatal outcomes were unaffected. CONCLUSIONS: Induction of labor is not associated with increased blood loss after delivery and should not be regarded as a risk factor for postpartum hemorrhage. BioMed Central 2019-07-25 /pmc/articles/PMC6659310/ /pubmed/31345178 http://dx.doi.org/10.1186/s12884-019-2410-8 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Brun, Romana
Spoerri, Emilian
Schäffer, Leonhard
Zimmermann, Roland
Haslinger, Christian
Induction of labor and postpartum blood loss
title Induction of labor and postpartum blood loss
title_full Induction of labor and postpartum blood loss
title_fullStr Induction of labor and postpartum blood loss
title_full_unstemmed Induction of labor and postpartum blood loss
title_short Induction of labor and postpartum blood loss
title_sort induction of labor and postpartum blood loss
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659310/
https://www.ncbi.nlm.nih.gov/pubmed/31345178
http://dx.doi.org/10.1186/s12884-019-2410-8
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