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Real-time detection of antibiotics cytotoxicity in rabbit periosteal cells using microfluidic devices with comparison to conventional culture assays

BACKGROUND: Local antibiotic application has been widely used in orthopedic surgery. The dose-related toxicity of antibiotics towards periosteal tissues and resulting effects on osteogenic expression are yet to be studied. METHODS: Periosteal cells harvested from the medial tibia of New Zealand Whit...

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Detalles Bibliográficos
Autores principales: Chiu, Chih-Hao, Lei, Kin Fong, Chan, Yi-Sheng, Ueng, Steve W. N., Chen, Alvin Chao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659314/
https://www.ncbi.nlm.nih.gov/pubmed/31349830
http://dx.doi.org/10.1186/s12891-019-2705-y