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Real-time detection of antibiotics cytotoxicity in rabbit periosteal cells using microfluidic devices with comparison to conventional culture assays
BACKGROUND: Local antibiotic application has been widely used in orthopedic surgery. The dose-related toxicity of antibiotics towards periosteal tissues and resulting effects on osteogenic expression are yet to be studied. METHODS: Periosteal cells harvested from the medial tibia of New Zealand Whit...
Autores principales: | Chiu, Chih-Hao, Lei, Kin Fong, Chan, Yi-Sheng, Ueng, Steve W. N., Chen, Alvin Chao-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659314/ https://www.ncbi.nlm.nih.gov/pubmed/31349830 http://dx.doi.org/10.1186/s12891-019-2705-y |
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