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Crystal structure of pirfenidone (5-methyl-1-phenyl-1H-pyridin-2-one): an active pharmaceutical ingredient (API)

The crystal structure of pirfenidone, C(12)H(11)NO [alternative name: 5-methyl-1-phenyl­pyridin-2(1H)-one], an active pharmaceutical ingredient (API) approved in Europe and Japan for the treatment of Idiopathic pulmonary fibrosis (IPF), is reported here for the first time. It was crystallized from t...

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Detalles Bibliográficos
Autores principales: Barbero, Mauro, Mossotti, Matteo, Sironi, Angelo, Giovenzana, Giovanni Battista, Colombo, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659322/
https://www.ncbi.nlm.nih.gov/pubmed/31392009
http://dx.doi.org/10.1107/S2056989019006418