Detecting and correcting for bias in Mendelian randomization analyses using Gene-by-Environment interactions

BACKGROUND: Mendelian randomization (MR) has developed into an established method for strengthening causal inference and estimating causal effects, largely due to the proliferation of genome-wide association studies. However, genetic instruments remain controversial, as horizontal pleiotropic effect...

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Detalles Bibliográficos
Autores principales: Spiller, Wes, Slichter, David, Bowden, Jack, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Mendelian Randomization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659360/
https://www.ncbi.nlm.nih.gov/pubmed/30462199
http://dx.doi.org/10.1093/ije/dyy204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659360/
https://www.ncbi.nlm.nih.gov/pubmed/30462199
http://dx.doi.org/10.1093/ije/dyy204

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