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Detecting and correcting for bias in Mendelian randomization analyses using Gene-by-Environment interactions
BACKGROUND: Mendelian randomization (MR) has developed into an established method for strengthening causal inference and estimating causal effects, largely due to the proliferation of genome-wide association studies. However, genetic instruments remain controversial, as horizontal pleiotropic effect...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659360/ https://www.ncbi.nlm.nih.gov/pubmed/30462199 http://dx.doi.org/10.1093/ije/dyy204 |