The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis

BACKGROUND: Evidence linking breast size to breast cancer risk has been inconsistent, and its interpretation is often hampered by confounding factors such as body mass index (BMI). Here, we used linkage disequilibrium score regression and two-sample Mendelian randomization (MR) to examine the geneti...

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Detalles Bibliográficos
Autores principales: Ooi, Brandon Nick Sern, Loh, Huiwen, Ho, Peh Joo, Milne, Roger L, Giles, Graham, Gao, Chi, Kraft, Peter, John, Esther M, Swerdlow, Anthony, Brenner, Hermann, Wu, Anna H, Haiman, Christopher, Evans, D Gareth, Zheng, Wei, Fasching, Peter A, Castelao, Jose Esteban, Kwong, Ava, Shen, Xia, Czene, Kamila, Hall, Per, Dunning, Alison, Easton, Douglas, Hartman, Mikael, Li, Jingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Mendelian Randomization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659372/
https://www.ncbi.nlm.nih.gov/pubmed/31243447
http://dx.doi.org/10.1093/ije/dyz124

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