Cargando…

Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans

Several vaccines are approved in the United States for seasonal influenza vaccination every year. Here we compare the impact of repeat influenza vaccination on hemagglutination inhibition (HI) titers, antibody binding and affinity maturation to individual hemagglutinin (HA) domains, HA1 and HA2, acr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khurana, Surender, Hahn, Megan, Coyle, Elizabeth M., King, Lisa R., Lin, Tsai-Lien, Treanor, John, Sant, Andrea, Golding, Hana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659679/ https://www.ncbi.nlm.nih.gov/pubmed/31350391 http://dx.doi.org/10.1038/s41467-019-11296-5

Ejemplares similares

Heterologous Prime-Boost Vaccination with MF59-Adjuvanted H5 Vaccines Promotes Antibody Affinity Maturation towards the Hemagglutinin HA1 Domain and Broad H5N1 Cross-Clade Neutralization
por: Khurana, Surender, et al.
Publicado: (2014)

AID Activity in B Cells Strongly Correlates with Polyclonal Antibody Affinity Maturation in-vivo Following Pandemic 2009-H1N1 Vaccination in Humans
por: Khurana, Surender, et al.
Publicado: (2012)

Oral Priming with Replicating Adenovirus Serotype 4 Followed by Subunit H5N1 Vaccine Boost Promotes Antibody Affinity Maturation and Expands H5N1 Cross-Clade Neutralization
por: Khurana, Surender, et al.
Publicado: (2015)

AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization
por: Khurana, Surender, et al.
Publicado: (2018)

Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients
por: Tang, Juanjie, et al.
Publicado: (2021)

Antibody affinity maturation and cross-variant activity following SARS-CoV-2 mRNA vaccination: Impact of prior exposure and sex
por: Tang, Juanjie, et al.
Publicado: (2021)

Autoreactivity of Broadly Neutralizing Influenza Human Antibodies to Human Tissues and Human Proteins
por: Khurana, Surender, et al.
Publicado: (2020)

Comparison of SARS-CoV-2 Hyperimmune Immunoglobulins Following Infection Plus Vaccination vs Infection
por: Bellusci, Lorenza, et al.
Publicado: (2023)

A Rapid Flp-In System for Expression of Secreted H5N1 Influenza Hemagglutinin Vaccine Immunogen in Mammalian Cells
por: Lu, Hanxin, et al.
Publicado: (2011)

Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA.1, BA.2 and BA.3 following third mRNA vaccination
por: Bellusci, Lorenza, et al.
Publicado: (2022)

Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model
por: Fuentes, Sandra, et al.
Publicado: (2017)

Immune Response to SARS-CoV-2 Vaccine and Following Breakthrough Omicron Infection in an Autoimmune Patient with Hashimoto’s Thyroiditis, Pernicious Anemia, and Chronic Atrophic Autoimmune Gastritis: A Case Report
por: Cluff, Emily, et al.
Publicado: (2022)

A Simple Flow-Cytometric Method Measuring B Cell Surface Immunoglobulin Avidity Enables Characterization of Affinity Maturation to Influenza A Virus
por: Frank, Gregory M., et al.
Publicado: (2015)

Antigenic Fingerprinting following Primary RSV Infection in Young Children Identifies Novel Antigenic Sites and Reveals Unlinked Evolution of Human Antibody Repertoires to Fusion and Attachment Glycoproteins
por: Fuentes, Sandra, et al.
Publicado: (2016)

Protective antigenic sites in respiratory syncytial virus G attachment protein outside the central conserved and cysteine noose domains
por: Lee, Jeehyun, et al.
Publicado: (2018)

Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets
por: Khurana, Surender, et al.
Publicado: (2009)

Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus
por: Khurana, Surender, et al.
Publicado: (2010)

Neutralization of SARS-CoV-2 Omicron after vaccination of patients with myelodysplastic syndromes or acute myeloid leukemia
por: Bellusci, Lorenza, et al.
Publicado: (2022)

Therapeutic potential of convalescent plasma and hyperimmune immunoglobulins against SARS-CoV-2 BQ.1, BQ.1.1, and XBB variants
por: Bellusci, Lorenza, et al.
Publicado: (2023)

Development and Regulation of Novel Influenza Virus Vaccines: A United States Young Scientist Perspective
por: Khurana, Surender
Publicado: (2018)

Human Antibody Repertoire following Ebola Virus Infection and Vaccination
por: Fuentes, Sandra, et al.
Publicado: (2020)

ICOS(+)PD-1(+)CXCR3(+) T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination
por: Bentebibel, Salah-Eddine, et al.
Publicado: (2016)

Protective antigenic sites identified in respiratory syncytial virus fusion protein reveals importance of p27 domain
por: Lee, Jeehyun, et al.
Publicado: (2021)

Immunological Memory and Affinity Maturation After Vaccination in Patients With Propionic Acidemia
por: Zlamy, Manuela, et al.
Publicado: (2022)

Impact of Convalescent Plasma Therapy on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Profile in Coronavirus Disease 2019 (COVID-19) Patients
por: Tang, Juanjie, et al.
Publicado: (2021)

Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits
por: Ravichandran, Supriya, et al.
Publicado: (2020)

Effect of Influenza A(H5N1) Vaccine Prepandemic Priming on CD4(+) T-Cell Responses
por: Nayak, Jennifer L., et al.
Publicado: (2015)

The Cutter Incident: How America’s First Polio Vaccine Led to the Growing Vaccine Crisis
por: Treanor, John
Publicado: (2006)

Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies
por: Ravichandran, Supriya, et al.
Publicado: (2022)

Patients with MS under daclizumab therapy mount normal immune responses to influenza vaccination
por: Lin, Yen Chih, et al.
Publicado: (2016)

FluBlok, a recombinant hemagglutinin influenza vaccine
por: Cox, Manon M.J., et al.
Publicado: (2008)

Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans
por: Richards, K. A., et al.
Publicado: (2020)

Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2–infected individuals reveal unlinked immune signatures
por: Ravichandran, Supriya, et al.
Publicado: (2021)

The Effects of Imprinting and Repeated Seasonal Influenza Vaccination on Adaptive Immunity after Influenza Vaccination
por: Sherman, Amy C., et al.
Publicado: (2020)

Affinity maturation in a human humoral response to influenza hemagglutinin
por: McCarthy, Kevin R., et al.
Publicado: (2019)

Bacteriophage T4 Vaccine Platform for Next-Generation Influenza Vaccine Development
por: Li, Mengling, et al.
Publicado: (2021)

Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial
por: Rouphael, Nadine G., et al.
Publicado: (2021)

The impact of repeated vaccination on relative influenza vaccine effectiveness among vaccinated adults in the United Kingdom
por: Lim, Wey Wen, et al.
Publicado: (2022)

Promising Adjuvants and Platforms for Influenza Vaccine Development
por: Zhu, Wandi, et al.
Publicado: (2021)

A stochastic B cell affinity maturation model to characterize mechanisms of protection for tetravalent dengue vaccine constructs
por: Pannala, Venkat R., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3mj7n1p24piq13mhvl4p5dn9h6