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Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans

Several vaccines are approved in the United States for seasonal influenza vaccination every year. Here we compare the impact of repeat influenza vaccination on hemagglutination inhibition (HI) titers, antibody binding and affinity maturation to individual hemagglutinin (HA) domains, HA1 and HA2, acr...

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Detalles Bibliográficos
Autores principales:	Khurana, Surender, Hahn, Megan, Coyle, Elizabeth M., King, Lisa R., Lin, Tsai-Lien, Treanor, John, Sant, Andrea, Golding, Hana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659679/ https://www.ncbi.nlm.nih.gov/pubmed/31350391 http://dx.doi.org/10.1038/s41467-019-11296-5

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