The histone methyltransferase Setd2 is indispensable for V(D)J recombination

The diverse repertoire of T cell receptors (TCR) and immunoglobulins is generated through the somatic rearrangement of respective V, D and J gene segments, termed V(D)J recombination, during early T or B cell development. However, epigenetic regulation of V(D)J recombination is still not fully under...

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Detalles Bibliográficos
Autores principales: Ji, Zhongzhong, Sheng, Yaru, Miao, Juju, Li, Xiaoxia, Zhao, Huifang, Wang, Jinming, Cheng, Chaping, Wang, Xue, Liu, Kaiyuan, Zhang, Kai, Xu, Longmei, Yao, Jufang, Shen, Lijing, Hou, Jian, Zhou, Wenhao, Sun, Jinqiao, Li, Li, Gao, Wei-Qiang, Zhu, Helen He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659703/
https://www.ncbi.nlm.nih.gov/pubmed/31350389
http://dx.doi.org/10.1038/s41467-019-11282-x

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