Cargando…
The phosphatase PPM1A inhibits triple negative breast cancer growth by blocking cell cycle progression
Estrogen receptor (ER)-negative, progesterone receptor (PR)-negative and HER2-negative, or “triple negative,” breast cancer (TNBC) is a poor prognosis clinical subtype that occurs more frequently in younger women and is commonly treated with toxic chemotherapy. Effective targeted therapy for TNBC is...
Autores principales: | Mazumdar, Abhijit, Tahaney, William M., Reddy Bollu, Lakshmi, Poage, Graham, Hill, Jamal, Zhang, Yun, Mills, Gordon B., Brown, Powel H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659706/ https://www.ncbi.nlm.nih.gov/pubmed/31372497 http://dx.doi.org/10.1038/s41523-019-0118-6 |
Ejemplares similares
-
380 The kinesin-like protein Kif11 is essential for the survival of TP53 mutant triple-negative breast cancer cells
por: Lanier, Amanda, et al.
Publicado: (2023) -
Mutant P53 induces MELK expression by release of wild-type P53-dependent suppression of FOXM1
por: Bollu, Lakshmi Reddy, et al.
Publicado: (2020) -
Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion
por: Mazumdar, Abhijit, et al.
Publicado: (2016) -
Revealing targeted therapeutic opportunities in triple-negative breast cancers: A new strategy
por: Poage, Graham M, et al.
Publicado: (2013) -
Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer
por: Mazumdar, Abhijit, et al.
Publicado: (2022)