Cargando…

The Efficacy of 2% Topical Rebamipide on Conjunctival Squamous Metaplasia and Goblet Cell Density in Dry Eye Disease

Purpose: To clarify the pharmacological effects of 2% rebamipide eye drops on mucosal membrane functions of the ocular surface epithelium, we investigated keratoconjunctival alterations at the cellular level in this study. Methods: Fifteen patients with definite dry eye disease were recruited from o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simsek, Cem, Dogru, Murat, Shinzawa, Megumi, Den, Seika, Kojima, Takashi, Iseda, Hiroyuki, Suzuki, Mai, Shibasaki, Yoshiyuki, Yoshida, Naoshi, Shimazaki, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659741/ https://www.ncbi.nlm.nih.gov/pubmed/31259647 http://dx.doi.org/10.1089/jop.2018.0130

Ejemplares similares

Effect of topical rebamipide on conjunctival goblet cell recovery after vitrectomy
por: Kato, Kumiko, et al.
Publicado: (2016)

The Effects of Rebamipide 2% Ophthalmic Solution Application on Murine Subbasal Corneal Nerves After Environmental Dry Eye Stress
por: Simsek, Cem, et al.
Publicado: (2019)

Epidermal Fatty Acid-Binding Protein: A Novel Marker in the Diagnosis of Dry Eye Disease in Sjögren Syndrome
por: Shinzawa, Megumi, et al.
Publicado: (2018)

The Impact of Noncontact Tonometry and Icare Rebound Tonometry on Tear Stability and Dry Eye Clinical Practice
por: Dogru, Murat, et al.
Publicado: (2022)

Current Management and Treatment of Dry Eye Disease
por: Şimşek, Cem, et al.
Publicado: (2018)

Histological observation of goblet cells following topical rebamipide treatment of the human ocular surface: A case report
por: KASE, SATORU, et al.
Publicado: (2015)

In vivo fluorescence imaging of conjunctival goblet cells
por: Kim, Seonghan, et al.
Publicado: (2019)

The Application of in vivo laser scanning confocal microscopy as a tool of conjunctival in vivo cytology in the diagnosis of dry eye ocular surface disease
por: Kojima, Takashi, et al.
Publicado: (2010)

Modulation of Conjunctival Goblet Cell Function by Inflammatory Cytokines
por: Contreras-Ruiz, L., et al.
Publicado: (2013)

The protective role of conjunctival goblet cell mucin sialylation
por: Matsuzawa, Moe, et al.
Publicado: (2023)

Bioelectric Responses of Conjunctival Goblet Cells to Dry Eye: Impact of Ion Channels on Exocytotic Function and Viability
por: Puro, Donald G.
Publicado: (2020)

Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
por: Yamazoe, Katsuya, et al.
Publicado: (2011)

Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers
por: Uchino, Yuichi, et al.
Publicado: (2016)

Evaluation of conjunctival inflammatory status by confocal scanning laser microscopy and conjunctival brush cytology in patients with atopic keratoconjunctivitis (AKC)
por: Wakamatsu, Tais Hitomi, et al.
Publicado: (2009)

A prospective, randomized clinical study comparing accelerated corneal collagen crosslinking with 5% NaCl hypertonic saline for bullous keratopathy in Asian eyes
por: Kasai, Kozue, et al.
Publicado: (2019)

The effects of 3% diquafosol sodium application on the tear functions and ocular surface of the Cu,Zn-superoxide dismutase-1 (Sod1)–knockout mice
por: Kojima, Takashi, et al.
Publicado: (2014)

Dry eye in rheumatoid arthritis patients under TNF-inhibitors: conjunctival goblet cell as an early ocular biomarker
por: Usuba, Fany Solange, et al.
Publicado: (2020)

Immunomodulatory Cross-Talk between Conjunctival Goblet Cells and Dendritic Cells
por: Contreras-Ruiz, Laura, et al.
Publicado: (2015)

Context-Dependent Regulation of Conjunctival Goblet Cell Function by Allergic Mediators
por: García-Posadas, Laura, et al.
Publicado: (2018)

Effectiveness of bandage contact lens application in corneal epithelialization and pain alleviation following corneal transplantation; prospective, randomized clinical trial
por: Shimazaki, Jun, et al.
Publicado: (2016)

High expression of sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia
por: Xu, Chengyun, et al.
Publicado: (2018)

LKB1 deficiency upregulates RELM-α to drive airway goblet cell metaplasia
por: Li, Yu, et al.
Publicado: (2021)

Efficacy of Rebamipide Instillation for Contact Lens Discomfort With Dry Eye
por: Igarashi, Tsutomu, et al.
Publicado: (2018)

Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes
por: Shrivastava, Saurabh, et al.
Publicado: (2018)

Corneal In Vivo Laser-Scanning Confocal Microscopy Findings in Dry Eye Patients with Sjögren’s Syndrome
por: Matsumoto, Yukihiro, et al.
Publicado: (2020)

Salivary and Lacrimal Gland Alterations of the Epidermal Fatty Acid-Binding Protein (E-FABP) in Non-Obese Diabetic Mice †
por: Dogru, Murat, et al.
Publicado: (2022)

The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways
por: Boucherat, Olivier, et al.
Publicado: (2012)

SUMOylation of Rho-associated protein kinase 2 induces goblet cell metaplasia in allergic airways
por: Tan, Dan, et al.
Publicado: (2023)

Topical rebamipide improves lid wiper epitheliopathy
por: Itakura, Hirotaka, et al.
Publicado: (2013)

The Effect of Rebamipide on Refractive Accuracy of Cataract Surgery in Patients with Dry Eye
por: Teshigawara, Takeshi, et al.
Publicado: (2022)

Ambient Levels of Air Pollution Induce Goblet-Cell Hyperplasia in Human Conjunctival Epithelium
por: Novaes, Priscila, et al.
Publicado: (2007)

Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells
por: McGilligan, Victoria E., et al.
Publicado: (2013)

Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion
por: He, Min, et al.
Publicado: (2016)

Goblet cell scarcity and conjunctival inflammation during treatment with dupilumab in patients with atopic dermatitis
por: Bakker, D.S., et al.
Publicado: (2019)

Inhibition of microRNA-328 Increases Ocular Mucin Expression and Conjunctival Goblet Cells
por: Choo, Jackson, et al.
Publicado: (2023)

Efficacy and safety of topical 2% rebamipide ophthalmic suspension in dry eye disease at tertiary care centre
por: Jain, Kalpna, et al.
Publicado: (2023)

Rebamipide ophthalmic suspension for the treatment of dry eye syndrome: a critical appraisal
por: Kashima, Tomoyuki, et al.
Publicado: (2014)

Effectiveness and relevant factors of 2 % rebamipide ophthalmic suspension treatment in dry eye
por: Ueda, Kaori, et al.
Publicado: (2015)

Long-term Rebamipide and Diquafosol in Two Cases of Immune-Mediated Dry Eye
por: Yamane, Mio, et al.
Publicado: (2015)

Feasibility of Strip Meniscometry for Tear Volume Evaluation in Lacrimal Passage Obstruction
por: Osawa, Ikubun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t3el2f3rm8ai5mcpokdtqqo134