Cargando…
Estradiol promotes the progression of ER+ breast cancer through methylation-mediated RSK4 inactivation
Background: It’s well documented that estrogen plays a vital role in breast cancer progression, but the molecular mechanisms underlying it still remains incompletely clear. This study aimed to explore whether ribosomal protein S6 kinase 4 (RSK4) was involved in estrogen-induced breast cancer develop...
Autores principales: | Li, Qiuyun, Gao, Hui, Yang, Huawei, Wei, Wei, Jiang, Yi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659789/ https://www.ncbi.nlm.nih.gov/pubmed/31413588 http://dx.doi.org/10.2147/OTT.S208988 |
Ejemplares similares
-
Promoter methylation and expression changes of BRCA1 in cancerous tissues of patients with sporadic breast cancer
por: LI, QIUYUN, et al.
Publicado: (2015) -
RSK2 and ERα comrades-in-arms in homeostasis and transformation
por: Ludwik, Katarzyna A., et al.
Publicado: (2020) -
17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression
por: Huang, Quanfu, et al.
Publicado: (2018) -
Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer
por: Moon, Hyeong-Gon, et al.
Publicado: (2012) -
RSK-c-Fos in KSHV lytic progression
por: Li, Xiaojuan, et al.
Publicado: (2015)