Targeting HMGB1 by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs and systems. Mesenchymal stem cells (MSCs) from SLE patients have demonstrated defects such as impaired growth, senescence phenotype and immunomodulatory functions. Some studies have suggested the close conn...

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Detalles Bibliográficos
Autores principales: Ji, Juan, Fu, Ting, Dong, Chen, Zhu, Wenyan, Yang, Junling, Kong, Xiaoli, Zhang, Zhongyuan, Bao, Yanfeng, Zhao, Rui, Ge, Xinyu, Sha, Xiaoqi, Lu, Zhimin, Li, Jing, Gu, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056/
https://www.ncbi.nlm.nih.gov/pubmed/31303606
http://dx.doi.org/10.18632/aging.102052

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