Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of microenvironment associated with COPD

Evidences have shown a strong link between particulate matter (PM) and increased risk in human mortality and morbidity, including asthma, chronic obstructive pulmonary disease (COPD), respiratory infection, and lung cancer. However, the underlying toxicologic mechanisms remain largely unknown. Utili...

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Detalles Bibliográficos
Autores principales: Tien, Chia-Ping, Chen, Chia-Hung, Lin, Wen-Yuan, Liu, Chiu-Shong, Liu, Ko-Jiunn, Hsiao, Michael, Chang, Yu-Chan, Hung, Shih-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660058/
https://www.ncbi.nlm.nih.gov/pubmed/31299012
http://dx.doi.org/10.18632/aging.102077

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