Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report

Pulmonary sclerosing pneumocytoma (PSP) is pathologically classified as an adenoma and behaves in a benign manner. However, some cases of PSP displayed pathologically malignant behavior, such as lymph node metastasis and necrosis. A 64-year-old woman was referred to our hospital complaining of a cou...

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Detalles Bibliográficos
Autores principales: Sakai, Takashi, Miyoshi, Tomohiro, Umemura, Shigeki, Suzuki, Jun, Nakasone, Shoko, Okada, Satoshi, Tane, Kenta, Aokage, Keiju, Goto, Koichi, Motoi, Noriko, Ishii, Genichiro, Tsuboi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660061/
https://www.ncbi.nlm.nih.gov/pubmed/31428771
http://dx.doi.org/10.1093/omcr/omz066
Descripción
Sumario:Pulmonary sclerosing pneumocytoma (PSP) is pathologically classified as an adenoma and behaves in a benign manner. However, some cases of PSP displayed pathologically malignant behavior, such as lymph node metastasis and necrosis. A 64-year-old woman was referred to our hospital complaining of a cough and breathlessness. Histopathological analysis of the resected specimen by left pneumonectomy and lymph node dissection revealed a large PSP measuring 15 × 14 cm in size, with massive necrosis and vascular invasion. This case was the largest ever reported and suggested that clinico-histological presentation of PSP sometimes showed an aggressive phenotype like advanced lung cancer.

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