Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report

Pulmonary sclerosing pneumocytoma (PSP) is pathologically classified as an adenoma and behaves in a benign manner. However, some cases of PSP displayed pathologically malignant behavior, such as lymph node metastasis and necrosis. A 64-year-old woman was referred to our hospital complaining of a cou...

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Autores principales: Sakai, Takashi, Miyoshi, Tomohiro, Umemura, Shigeki, Suzuki, Jun, Nakasone, Shoko, Okada, Satoshi, Tane, Kenta, Aokage, Keiju, Goto, Koichi, Motoi, Noriko, Ishii, Genichiro, Tsuboi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660061/
https://www.ncbi.nlm.nih.gov/pubmed/31428771
http://dx.doi.org/10.1093/omcr/omz066
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author Sakai, Takashi
Miyoshi, Tomohiro
Umemura, Shigeki
Suzuki, Jun
Nakasone, Shoko
Okada, Satoshi
Tane, Kenta
Aokage, Keiju
Goto, Koichi
Motoi, Noriko
Ishii, Genichiro
Tsuboi, Masahiro
author_facet Sakai, Takashi
Miyoshi, Tomohiro
Umemura, Shigeki
Suzuki, Jun
Nakasone, Shoko
Okada, Satoshi
Tane, Kenta
Aokage, Keiju
Goto, Koichi
Motoi, Noriko
Ishii, Genichiro
Tsuboi, Masahiro
author_sort Sakai, Takashi
collection PubMed
description Pulmonary sclerosing pneumocytoma (PSP) is pathologically classified as an adenoma and behaves in a benign manner. However, some cases of PSP displayed pathologically malignant behavior, such as lymph node metastasis and necrosis. A 64-year-old woman was referred to our hospital complaining of a cough and breathlessness. Histopathological analysis of the resected specimen by left pneumonectomy and lymph node dissection revealed a large PSP measuring 15 × 14 cm in size, with massive necrosis and vascular invasion. This case was the largest ever reported and suggested that clinico-histological presentation of PSP sometimes showed an aggressive phenotype like advanced lung cancer.
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spelling pubmed-66600612019-08-02 Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report Sakai, Takashi Miyoshi, Tomohiro Umemura, Shigeki Suzuki, Jun Nakasone, Shoko Okada, Satoshi Tane, Kenta Aokage, Keiju Goto, Koichi Motoi, Noriko Ishii, Genichiro Tsuboi, Masahiro Oxf Med Case Reports Case Report Pulmonary sclerosing pneumocytoma (PSP) is pathologically classified as an adenoma and behaves in a benign manner. However, some cases of PSP displayed pathologically malignant behavior, such as lymph node metastasis and necrosis. A 64-year-old woman was referred to our hospital complaining of a cough and breathlessness. Histopathological analysis of the resected specimen by left pneumonectomy and lymph node dissection revealed a large PSP measuring 15 × 14 cm in size, with massive necrosis and vascular invasion. This case was the largest ever reported and suggested that clinico-histological presentation of PSP sometimes showed an aggressive phenotype like advanced lung cancer. Oxford University Press 2019-07-26 /pmc/articles/PMC6660061/ /pubmed/31428771 http://dx.doi.org/10.1093/omcr/omz066 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Sakai, Takashi
Miyoshi, Tomohiro
Umemura, Shigeki
Suzuki, Jun
Nakasone, Shoko
Okada, Satoshi
Tane, Kenta
Aokage, Keiju
Goto, Koichi
Motoi, Noriko
Ishii, Genichiro
Tsuboi, Masahiro
Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
title Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
title_full Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
title_fullStr Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
title_full_unstemmed Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
title_short Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
title_sort large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660061/
https://www.ncbi.nlm.nih.gov/pubmed/31428771
http://dx.doi.org/10.1093/omcr/omz066
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