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Metabolic engineering of Rhodococcus ruber Chol-4: A cell factory for testosterone production
Rhodococcus ruber Chol-4 is a potent steroid degrader that has a great potential as a biotechnological tool. As proof of concept, this work presents testosterone production from 4-androstene-3,17-dione by tailoring innate catabolic enzymes of the steroid catabolism inside the strain. A R. ruber quad...
Autores principales: | Guevara, Govinda, Olortegui Flores, Yamileth, Fernández de las Heras, Laura, Perera, Julián, Navarro Llorens, Juana María |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660089/ https://www.ncbi.nlm.nih.gov/pubmed/31348804 http://dx.doi.org/10.1371/journal.pone.0220492 |
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