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Analyzing pharmacological intervention points: A method to calculate external stimuli to switch between steady states in regulatory networks
Once biological systems are modeled by regulatory networks, the next step is to include external stimuli, which model the experimental possibilities to affect the activity level of certain network’s nodes, in a mathematical framework. Then, this framework can be interpreted as a mathematical optimal...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660093/ https://www.ncbi.nlm.nih.gov/pubmed/31310618 http://dx.doi.org/10.1371/journal.pcbi.1007075 |