Cargando…

Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity

Diabetes mellitus (DM) increases risk for pulmonary tuberculosis (TB) and adverse treatment outcomes. Systemic hyper-inflammation is characteristic in people with TB and concurrent DM (TBDM) at baseline, but the impact of TB treatment on this pattern has not been determined. We measured 17 plasma cy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Nathella Pavan, Fukutani, Kiyoshi F, Shruthi, Basavaradhya S, Alves, Thabata, Silveira-Mattos, Paulo S, Rocha, Michael S, West, Kim, Natarajan, Mohan, Viswanathan, Vijay, Babu, Subash, Andrade, Bruno B, Kornfeld, Hardy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660216/ https://www.ncbi.nlm.nih.gov/pubmed/31271354 http://dx.doi.org/10.7554/eLife.46477

Ejemplares similares

Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis
por: Kumar, Nathella P., et al.
Publicado: (2019)

Plasma Eicosanoid Levels in Tuberculosis and Tuberculosis-Diabetes Co-morbidity Are Associated With Lung Pathology and Bacterial Burden
por: Pavan Kumar, Nathella, et al.
Publicado: (2019)

Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy
por: Kumar, Nathella Pavan, et al.
Publicado: (2019)

Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment
por: Kumar, Nathella P., et al.
Publicado: (2018)

Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications
por: Prada-Medina, Cesar A., et al.
Publicado: (2017)

Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Heightened circulating levels of antimicrobial peptides in tuberculosis—Diabetes co-morbidity and reversal upon treatment
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Acute Phase Proteins Are Baseline Predictors of Tuberculosis Treatment Failure
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Chitinase and indoleamine 2, 3-dioxygenase are prognostic biomarkers for unfavorable treatment outcomes in pulmonary tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction
por: Queiroz, Artur T. L., et al.
Publicado: (2023)

Coincident Pre-Diabetes Is Associated with Dysregulated Cytokine Responses in Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2014)

Association of Plasma Matrix Metalloproteinase and Tissue Inhibitors of Matrix Metalloproteinase Levels With Adverse Treatment Outcomes Among Patients With Pulmonary Tuberculosis
por: Kumar, Nathella P., et al.
Publicado: (2020)

Aging increases the systemic molecular degree of inflammatory perturbation in patients with tuberculosis
por: Oliveira-de-Souza, Deivide, et al.
Publicado: (2020)

High Dimensionality Reduction and Immune Phenotyping of Natural Killer and Invariant Natural Killer Cells in Latent Tuberculosis-Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2022)

Impact of diabetes mellitus on immunity to latent tuberculosis infection
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

Decreased Frequencies of Gamma/Delta T Cells Expressing Th1/Th17 Cytokine, Cytotoxic, and Immune Markers in Latent Tuberculosis-Diabetes/Pre-Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2021)

Multi-Dimensionality Immunophenotyping Analyses of MAIT Cells Expressing Th1/Th17 Cytokines and Cytotoxic Markers in Latent Tuberculosis Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2022)

Augmented Innate and Adaptive Immune Responses Under Conditions of Diabetes–Filariasis Comorbidity
por: Sibi, Joy Manohar, et al.
Publicado: (2021)

New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis
por: Striz, Ilja, et al.
Publicado: (2023)

Emphysematous pyelonephritis with gas in inferior vena cava
por: Vaddi, Chandra Mohan, et al.
Publicado: (2020)

Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2016)

Diminished plasma levels of common γ-chain cytokines in pulmonary tuberculosis and reversal following treatment
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Ureteral embolisation for the management of persistent uretero-ileal anastomotic leak
por: Chau, Matthew, et al.
Publicado: (2022)

Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy
por: Cunha, Pedro P, et al.
Publicado: (2023)

Prediabetes is associated with the modulation of antigen-specific Th1/Tc1 and Th17/Tc17 responses in latent Mycobacterium tuberculosis infection
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection
por: Cheekatla, Satyanarayana Swamy, et al.
Publicado: (2016)

Memory persistence and differentiation into antibody-secreting cells accompanied by positive selection in longitudinal BCR repertoires
por: Mikelov, Artem, et al.
Publicado: (2022)

Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis
por: Mijnheer, Gerdien, et al.
Publicado: (2023)

Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells
por: Morgun, Eva, et al.
Publicado: (2023)

Inhibitory IL-10-producing CD4(+) T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1
por: Clement, Mathew, et al.
Publicado: (2023)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

Proteomics: A new perspective for cancer
por: Shruthi, Basavaradhya Sahukar, et al.
Publicado: (2016)

A rare case of tubercular recto-prostatic urethral fistula with tuberculous orchitis
por: Pathak, Niramya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_uqiepoanggdl4sd8her0qc7g20