Cargando…

Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content

Full dataset used to evaluate the spray-drying process parameters on the preparation of a micronized powder made of maltodextrin (MDX) is herein reported. The process parameters (namely, feed flow rate (FFR); inlet temperature (T(in)); nozzle pressure (P(N)); noozle diameter (D(N)) and difference of...

Descripción completa

Detalles Bibliográficos
Autores principales: Magri, Giulia, Franzé, Silvia, Musazzi, Umberto M., Selmin, Francesca, Cilurzo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660546/
https://www.ncbi.nlm.nih.gov/pubmed/31372438
http://dx.doi.org/10.1016/j.dib.2019.103792
_version_ 1783439318620045312
author Magri, Giulia
Franzé, Silvia
Musazzi, Umberto M.
Selmin, Francesca
Cilurzo, Francesco
author_facet Magri, Giulia
Franzé, Silvia
Musazzi, Umberto M.
Selmin, Francesca
Cilurzo, Francesco
author_sort Magri, Giulia
collection PubMed
description Full dataset used to evaluate the spray-drying process parameters on the preparation of a micronized powder made of maltodextrin (MDX) is herein reported. The process parameters (namely, feed flow rate (FFR); inlet temperature (T(in)); nozzle pressure (P(N)); noozle diameter (D(N)) and difference of pressure between cyclone and chamber (ΔP)) were screened through a Central Composite Design (2(5−1); 2(∗)5; n(C)=2) using the following responses: product yield, powder size and size dispersity (span) and the outlet temperature of the exhausted air (T(out)). Data indicate that, in the considered range, only the product yield and the powder median diameter were influenced by the process. The product yield progressively increased on increasing inlet temperature and decreasing the amount or the size of droplets to be dried. The powder median diameter was positively influenced only by the nozzle diameter. This data presented in this article completes a wider work related on “Maltodextrins as drying auxiliary agent for the preparation of easily resuspendable nanoparticles” (Magri et al., 2019).
format Online
Article
Text
id pubmed-6660546
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-66605462019-08-01 Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content Magri, Giulia Franzé, Silvia Musazzi, Umberto M. Selmin, Francesca Cilurzo, Francesco Data Brief Pharmacology, Toxicology and Pharmaceutical Science Full dataset used to evaluate the spray-drying process parameters on the preparation of a micronized powder made of maltodextrin (MDX) is herein reported. The process parameters (namely, feed flow rate (FFR); inlet temperature (T(in)); nozzle pressure (P(N)); noozle diameter (D(N)) and difference of pressure between cyclone and chamber (ΔP)) were screened through a Central Composite Design (2(5−1); 2(∗)5; n(C)=2) using the following responses: product yield, powder size and size dispersity (span) and the outlet temperature of the exhausted air (T(out)). Data indicate that, in the considered range, only the product yield and the powder median diameter were influenced by the process. The product yield progressively increased on increasing inlet temperature and decreasing the amount or the size of droplets to be dried. The powder median diameter was positively influenced only by the nozzle diameter. This data presented in this article completes a wider work related on “Maltodextrins as drying auxiliary agent for the preparation of easily resuspendable nanoparticles” (Magri et al., 2019). Elsevier 2019-02-28 /pmc/articles/PMC6660546/ /pubmed/31372438 http://dx.doi.org/10.1016/j.dib.2019.103792 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Pharmacology, Toxicology and Pharmaceutical Science
Magri, Giulia
Franzé, Silvia
Musazzi, Umberto M.
Selmin, Francesca
Cilurzo, Francesco
Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
title Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
title_full Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
title_fullStr Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
title_full_unstemmed Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
title_short Data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
title_sort data on spray-drying processing to optimize the yield of materials sensitive to heat and moisture content
topic Pharmacology, Toxicology and Pharmaceutical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660546/
https://www.ncbi.nlm.nih.gov/pubmed/31372438
http://dx.doi.org/10.1016/j.dib.2019.103792
work_keys_str_mv AT magrigiulia dataonspraydryingprocessingtooptimizetheyieldofmaterialssensitivetoheatandmoisturecontent
AT franzesilvia dataonspraydryingprocessingtooptimizetheyieldofmaterialssensitivetoheatandmoisturecontent
AT musazziumbertom dataonspraydryingprocessingtooptimizetheyieldofmaterialssensitivetoheatandmoisturecontent
AT selminfrancesca dataonspraydryingprocessingtooptimizetheyieldofmaterialssensitivetoheatandmoisturecontent
AT cilurzofrancesco dataonspraydryingprocessingtooptimizetheyieldofmaterialssensitivetoheatandmoisturecontent